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Original Research 
RMJ. 2021; 46(4): 822-825


Clinical profile of intraocular tuberculosis patients and its relationship with pulmonary tuberculosis

Ahmad Zeeshan Jamil, Zahid Kamal, Muhammad Waseem, Muhammad Junaid Iqbal, Nauman Aziz, Muhammad Luqman Ali Bahoo.

Abstract
Objective: To describe the clinical profile of intraocular tuberculosis (TB) patients and its relationship with pulmonary TB.
Methodology: This cross-sectional descriptive study was conducted in ophthalmology department of district headquarter teaching hospital, Sahiwal Medical College, Sahiwal, Pakistan from January 2016 to December 2019. There were 48 patients with intraocular TB. History of past TB or contact with TB was recorded. Detailed ocular examination was performed. All patients were also examined by pulmonologist. Anti-tuberculosis therapy comprising of Isoniazid, Rifampicin, Pyrazinamide and Ethambutol was given to all the patients. Systemic corticosteroids were given to selected patients with intense intraocular inflammation involving macula, disc or blood vessels.
Results: Mean age of patients was 33.0413.66 years. Male were 31(64.6%). Out of 48 cases, 42(87.5%) had bilateral intraocular TB. Presenting complaints were decreased vision (81.3%), floaters (12.5%) and pain (6.3%). T-spot test was positive in 44(91.7%) cases. X-ray chest showed abnormal findings in 30(62.5%) cases. Anti-tuberculosis therapy resulted in complete resolution of intraocular inflammation in 93.7% cases. There was significant improvement in visual acuity after treatment.
Conclusion: Intraocular TB is not common in cases of active pulmonary TB. In most cases ophthalmologist was the first to make a diagnosis. Anti-tuberculosis therapy should be started in cases of intraocular inflammation where positive immunological laboratory tests and suggestive radiological findings were present. Management of intraocular inflammation with anti-tuberculosis therapy results in visual improvement, resolution of the disease and less frequent recurrences.

Key words: Choroiditis, tuberculosis, uveitis.


 
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How to Cite this Article
Pubmed Style

Jamil AZ, Kamal Z, Waseem M, Iqbal MJ, Aziz N, Bahoo MLA. Clinical profile of intraocular tuberculosis patients and its relationship with pulmonary tuberculosis. RMJ. 2021; 46(4): 822-825.


Web Style

Jamil AZ, Kamal Z, Waseem M, Iqbal MJ, Aziz N, Bahoo MLA. Clinical profile of intraocular tuberculosis patients and its relationship with pulmonary tuberculosis. http://www.rmj.org.pk/?mno=116509 [Access: October 14, 2021].


AMA (American Medical Association) Style

Jamil AZ, Kamal Z, Waseem M, Iqbal MJ, Aziz N, Bahoo MLA. Clinical profile of intraocular tuberculosis patients and its relationship with pulmonary tuberculosis. RMJ. 2021; 46(4): 822-825.



Vancouver/ICMJE Style

Jamil AZ, Kamal Z, Waseem M, Iqbal MJ, Aziz N, Bahoo MLA. Clinical profile of intraocular tuberculosis patients and its relationship with pulmonary tuberculosis. RMJ. (2021), [cited October 14, 2021]; 46(4): 822-825.



Harvard Style

Jamil, A. Z., Kamal, . Z., Waseem, . M., Iqbal, . M. J., Aziz, . N. & Bahoo, . M. L. A. (2021) Clinical profile of intraocular tuberculosis patients and its relationship with pulmonary tuberculosis. RMJ, 46 (4), 822-825.



Turabian Style

Jamil, Ahmad Zeeshan, Zahid Kamal, Muhammad Waseem, Muhammad Junaid Iqbal, Nauman Aziz, and Muhammad Luqman Ali Bahoo. 2021. Clinical profile of intraocular tuberculosis patients and its relationship with pulmonary tuberculosis. Rawal Medical Journal, 46 (4), 822-825.



Chicago Style

Jamil, Ahmad Zeeshan, Zahid Kamal, Muhammad Waseem, Muhammad Junaid Iqbal, Nauman Aziz, and Muhammad Luqman Ali Bahoo. "Clinical profile of intraocular tuberculosis patients and its relationship with pulmonary tuberculosis." Rawal Medical Journal 46 (2021), 822-825.



MLA (The Modern Language Association) Style

Jamil, Ahmad Zeeshan, Zahid Kamal, Muhammad Waseem, Muhammad Junaid Iqbal, Nauman Aziz, and Muhammad Luqman Ali Bahoo. "Clinical profile of intraocular tuberculosis patients and its relationship with pulmonary tuberculosis." Rawal Medical Journal 46.4 (2021), 822-825. Print.



APA (American Psychological Association) Style

Jamil, A. Z., Kamal, . Z., Waseem, . M., Iqbal, . M. J., Aziz, . N. & Bahoo, . M. L. A. (2021) Clinical profile of intraocular tuberculosis patients and its relationship with pulmonary tuberculosis. Rawal Medical Journal, 46 (4), 822-825.








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