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ISSN-0303-5212 |
| The
Journal of the Pakistan Medical Association Rawalpindi - Islamabad |
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Volume 34, Number 2, July - Dec. 2009 |  |
| Original article |
| Leptin levels during follicular and luteal phases of menstrual cycle |
| Riffat Shafi, Mohammad Nasir Afzal |
| Objective To explore the status of serum leptin levels in various phases of menstrual cycle in females of child bearing age. Method This observational study was carried out at Shifa College of Medicine, Islamabad in which serum leptin level of 83 females of reproductive age in various phases of female monthly cycle was measured, after taking an informed written consent. Results Mean serum leptin level of women during follicular phase was 54.6±33.4 ng/ml and luteal phase 53.5±38.8 ng/ml as assessed from last menstrual period (p=0.253). Serum Leptin level was found to be significantly higher in normal weight women during follicular phase (37.3±24.8 ng/ml) as compared to normal weight women in luteal phase (24.5±14.3 ng/ml) with p value 0.040. In overweight females, no significant difference was found between serum leptin level during follicular phase (78.84±29.07 ng/ml) and luteal phase (81.4±34.2 ng/ml), with p value 0.369. Conclusions We found no significant change in serum leptin level during follicular and luteal phases of menstrual cycles in healthy females. (Rawal Med J 2009;34:180-182). |
| Key Words: Leptin, menstrual cycle, follicular, luteal. |
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