Coagulability state in histopathologicaly and radiologicaly approved ovarian endomertiosis

Zahraa Najah Alzuhairi; Thura Abbas Fadhel; Intisar Ahmed Hasan

doi:10.5455/rmj20221126063638

Abstract
Objective: To determine the association between endometriosis and clotting abnormalities in relation to histopathological and ultrasound diagnosis.
Methodology: This cross-sectional study included 125 females with endometriosis seen at Baqubah teaching hospital from April 2021 and June 2022. The women's ages varied from 21 to 43 years. Seventy-five had ultrasound-detected ovarian cysts, 48 had MRI-confirmed ovarian endometriosis, and 50 normal women served as controls. All women had thrombin time, prothrombin time, activated partial thromboplastin time, D-dimer, plasma fibrinogen, and INR tested.
Results: The study had 125 females with mean age of 29±6 years. Histologically, 20.8% had endometrial gland and stroma and 11.2% had endometrial stroma. Endometriosis reduced PT, PTT, TT, and INR, but increased fibrinogen and D. dimer. There was significant association between ultrasound diagnosis and histopathological diagnosis of endometriosis.
Conclusion: PT, PTT, INR, Fibrinogen, and D. dimer levels differ between histology and ultrasonography endometriosis diagnoses in women. Endometriosis patients showed greater fibrinogen and D. dimer levels and reduced PT, PTT, TT, and INR (INR).

Key words: Coagulability state, histopathologicaly, radiologicaly, ovarian endomertiosis.

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