Factors affecting development of infected pancreatic necrosis after severe acute pancreatitis

Ahmad Kaleem; Ameer Afzal; Mohammad Sohail Asghar; Ahmad Rafique; Shahzad Yousaf; Yar Muhammad Khokhar

Abstract
Objective: To identify important patient factors in development of infected pancreatic necrosis after severe acute pancreatitis.
Methodology: A total of 105 patients of both gender in the department of Surgery, Mayo Hospital Lahore, with age range 18-80 years, from January to December 2019, were included in this study, using random sampling technique (95% confidence level.) Revised Atlanta classification was used to identify severe acute pancreatitis patients with Ranson score >3.
Results: Demographic history was obtained from the patient's records including contrast enhanced CT scans abdomen to check for pancreatic necrosis, infection, and CT-guided fine-needle aspiration cytology (FNAC) to verify infection. The contributing factors at the time of presentation such as gallstone, choledocholithiasis, alcoholism, trauma, drugs, infections, and malignancy were recorded with and without infected pancreatic necrosis. The CT severity index was used to predict adverse outcome, such as mortality with pancreatic necrosis. Data were analyzed using SPSS 21.
Conclusion: The main contributing factors in developing infected pancreatic necrosis in severe acute pancreatitis patients were gallstones, choledocholithiasis, alcoholism and idiopathic.

Key words: Infection, severe acute pancreatitis, CT, Ran son, gall-stone, idiopathic.

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