ISSN 0303-5212
 
2023, Vol: 48, Issue: 4
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Original Research 
RMJ. 2023; 48(4): 805-808


Clinical outcomes in type 2 diabetics switched to Insulin Degludec Aspart from conventional Premixed Insulin therapy

Komal Mumtaz Malik, Kulsoom Farhat, Muhammad Asghar Khan, Bilal Ahmad, Shabana Ali, Mudassar Noor.

Abstract
Objective: To compare the glycemic control of a newer insulin co-formulation, insulin degludec aspart with the conventional premixed insulin therapy, in type 2 diabetes mellitus.
Methodology: We included 120 participants with documented type 2 diabetes, taking premixed insulin therapy. They were divided into two groups; Group B participants were switched to once-daily insulin degludec aspart whereas those in group A continued receiving biphasic insulin aspart. Glycemic control was assessed with Hemoglobin A1c levels, fasting, and post-prandial plasma glucose concentrations of the participants during a 12-week study period.
Results: HbA1c, Fasting and 2-hour post prandial plasma glucose concentrations were significantly reduced in participants taking insulin degludec aspart (p<0.05).
Conclusion: Use of degludec aspart has simplified dosage method, increased treatment compliance, and produced better clinical outcomes in Pakistani population.

Key words: Biphasic insulin aspart, glycemic control, insulin degludec aspart, type 2 diabetes mellitus.


 
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How to Cite this Article
Pubmed Style

Malik KM, Farhat K, Khan MA, Ahmad B, Ali S, Noor M. Clinical outcomes in type 2 diabetics switched to Insulin Degludec Aspart from conventional Premixed Insulin therapy. RMJ. 2023; 48(4): 805-808.

Web Style

Malik KM, Farhat K, Khan MA, Ahmad B, Ali S, Noor M. Clinical outcomes in type 2 diabetics switched to Insulin Degludec Aspart from conventional Premixed Insulin therapy. https://www.rmj.org.pk/?mno=133351 [Access: November 22, 2023].

AMA (American Medical Association) Style

Malik KM, Farhat K, Khan MA, Ahmad B, Ali S, Noor M. Clinical outcomes in type 2 diabetics switched to Insulin Degludec Aspart from conventional Premixed Insulin therapy. RMJ. 2023; 48(4): 805-808.


Vancouver/ICMJE Style

Malik KM, Farhat K, Khan MA, Ahmad B, Ali S, Noor M. Clinical outcomes in type 2 diabetics switched to Insulin Degludec Aspart from conventional Premixed Insulin therapy. RMJ. (2023), [cited November 22, 2023]; 48(4): 805-808.


Harvard Style

Malik, K. M., Farhat, . K., Khan, . M. A., Ahmad, . B., Ali, . S. & Noor, . M. (2023) Clinical outcomes in type 2 diabetics switched to Insulin Degludec Aspart from conventional Premixed Insulin therapy. RMJ, 48 (4), 805-808.


Turabian Style

Malik, Komal Mumtaz, Kulsoom Farhat, Muhammad Asghar Khan, Bilal Ahmad, Shabana Ali, and Mudassar Noor. 2023. Clinical outcomes in type 2 diabetics switched to Insulin Degludec Aspart from conventional Premixed Insulin therapy. Rawal Medical Journal, 48 (4), 805-808.


Chicago Style

Malik, Komal Mumtaz, Kulsoom Farhat, Muhammad Asghar Khan, Bilal Ahmad, Shabana Ali, and Mudassar Noor. "Clinical outcomes in type 2 diabetics switched to Insulin Degludec Aspart from conventional Premixed Insulin therapy." Rawal Medical Journal 48 (2023), 805-808.


MLA (The Modern Language Association) Style

Malik, Komal Mumtaz, Kulsoom Farhat, Muhammad Asghar Khan, Bilal Ahmad, Shabana Ali, and Mudassar Noor. "Clinical outcomes in type 2 diabetics switched to Insulin Degludec Aspart from conventional Premixed Insulin therapy." Rawal Medical Journal 48.4 (2023), 805-808. Print.


APA (American Psychological Association) Style

Malik, K. M., Farhat, . K., Khan, . M. A., Ahmad, . B., Ali, . S. & Noor, . M. (2023) Clinical outcomes in type 2 diabetics switched to Insulin Degludec Aspart from conventional Premixed Insulin therapy. Rawal Medical Journal, 48 (4), 805-808.


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