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Original Research
Online Published: 29 Sep 2016
 
RMJ. 2016; 41(3): 300-303


In vitro activity of tetracyclines against multi-drug resistant Acinetobacter baumannii

Afreenish Hassan, Javaid Usman, Fatima Kaleem, Maria Mushtaq Gill, Ali Khalid, Muhammad Iqbal.


Abstract
Objective: To assess the in vitro sensitivity of multi drug resistant Acinetobacter baumannii (A.baumannii) against four tetracyclines.
Methodology: Routine clinical specimens were received from various wards of a tertiary care hospital from December 2009 to August 2010. A. baumannii was identified by using standard microbiological procedures. Minimum inhibitory concentration (MIC) was performed by using E-strips (AB-Biodisk) of tetracycline, minocycline, doxycyline and tigecycline for each isolate. Results were analyzed by using SPSS version 17.0.
Results: A total of fifty MDR Acinetobacter baumannii were analyzed during the study period. Among the four tetracyclines tested, minocycline was the most effective against MDR A. baumannii. Forty seven (94%) of the isolates were susceptible to minocycline with an MIC90 value 4 ug/mL.
Conclusion: Among tetracyclines, minocycline is an appropriate option against infections caused by MDR A. baumannii. This study will help our clinicians in finding a suitable treatment against such resistant bacteria.

Key words: Acinetobacter baumannii, Minocycline, Minimum inhibitory concentration (MIC)


 
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How to Cite this Article
Pubmed Style

Hassan A, Usman J, Kaleem F, Gill MM, Khalid A, Iqbal M. In vitro activity of tetracyclines against multi-drug resistant Acinetobacter baumannii. RMJ. 2016; 41(3): 300-303.

Web Style

Hassan A, Usman J, Kaleem F, Gill MM, Khalid A, Iqbal M. In vitro activity of tetracyclines against multi-drug resistant Acinetobacter baumannii. https://www.rmj.org.pk/?mno=196449 [Access: March 14, 2025].

AMA (American Medical Association) Style

Hassan A, Usman J, Kaleem F, Gill MM, Khalid A, Iqbal M. In vitro activity of tetracyclines against multi-drug resistant Acinetobacter baumannii. RMJ. 2016; 41(3): 300-303.


Vancouver/ICMJE Style

Hassan A, Usman J, Kaleem F, Gill MM, Khalid A, Iqbal M. In vitro activity of tetracyclines against multi-drug resistant Acinetobacter baumannii. RMJ. (2016), [cited March 14, 2025]; 41(3): 300-303.


Harvard Style

Hassan, A., Usman, . J., Kaleem, . F., Gill, . M. M., Khalid, . A. & Iqbal, . M. (2016) In vitro activity of tetracyclines against multi-drug resistant Acinetobacter baumannii. RMJ, 41 (3), 300-303.


Turabian Style

Hassan, Afreenish, Javaid Usman, Fatima Kaleem, Maria Mushtaq Gill, Ali Khalid, and Muhammad Iqbal. 2016. In vitro activity of tetracyclines against multi-drug resistant Acinetobacter baumannii. Rawal Medical Journal, 41 (3), 300-303.


Chicago Style

Hassan, Afreenish, Javaid Usman, Fatima Kaleem, Maria Mushtaq Gill, Ali Khalid, and Muhammad Iqbal. "In vitro activity of tetracyclines against multi-drug resistant Acinetobacter baumannii." Rawal Medical Journal 41 (2016), 300-303.


MLA (The Modern Language Association) Style

Hassan, Afreenish, Javaid Usman, Fatima Kaleem, Maria Mushtaq Gill, Ali Khalid, and Muhammad Iqbal. "In vitro activity of tetracyclines against multi-drug resistant Acinetobacter baumannii." Rawal Medical Journal 41.3 (2016), 300-303. Print.


APA (American Psychological Association) Style

Hassan, A., Usman, . J., Kaleem, . F., Gill, . M. M., Khalid, . A. & Iqbal, . M. (2016) In vitro activity of tetracyclines against multi-drug resistant Acinetobacter baumannii. Rawal Medical Journal, 41 (3), 300-303.


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