ISSN 0303-5212
 

Review Article 


Epigenetic modifications in hepatocellular carcinoma: A literature review

Taufik Sungkar, Darmadi Darmadi, Cennikon Pakpahan, Adriansyah Lubis.


Abstract
Understanding the epigenetic mechanisms has opened new avenues for the potential reversibility of epigenetic alterations and provided an opportunity to influence and control their unfavorable consequences. These findings not only aid in identifying novel targets for therapy but also enable the prediction of treatment response. Investigating epigenetics can uncover new targets for more effective therapeutic strategies and identify novel biomarkers for diagnosing HCC in the future.

Key words: Carcinoma, epigenetic, hepatocellular, therapy.


 
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How to Cite this Article
Pubmed Style

Sungkar T, Darmadi D, Pakpahan C, Lubis A. Epigenetic modifications in hepatocellular carcinoma: A literature review. RMJ. 2025; 50(2): 514-517. doi:10.5455/rmj.20240425033740


Web Style

Sungkar T, Darmadi D, Pakpahan C, Lubis A. Epigenetic modifications in hepatocellular carcinoma: A literature review. https://www.rmj.org.pk/?mno=199161 [Access: May 12, 2025]. doi:10.5455/rmj.20240425033740


AMA (American Medical Association) Style

Sungkar T, Darmadi D, Pakpahan C, Lubis A. Epigenetic modifications in hepatocellular carcinoma: A literature review. RMJ. 2025; 50(2): 514-517. doi:10.5455/rmj.20240425033740



Vancouver/ICMJE Style

Sungkar T, Darmadi D, Pakpahan C, Lubis A. Epigenetic modifications in hepatocellular carcinoma: A literature review. RMJ. (2025), [cited May 12, 2025]; 50(2): 514-517. doi:10.5455/rmj.20240425033740



Harvard Style

Sungkar, T., Darmadi, . D., Pakpahan, . C. & Lubis, . A. (2025) Epigenetic modifications in hepatocellular carcinoma: A literature review. RMJ, 50 (2), 514-517. doi:10.5455/rmj.20240425033740



Turabian Style

Sungkar, Taufik, Darmadi Darmadi, Cennikon Pakpahan, and Adriansyah Lubis. 2025. Epigenetic modifications in hepatocellular carcinoma: A literature review. Rawal Medical Journal, 50 (2), 514-517. doi:10.5455/rmj.20240425033740



Chicago Style

Sungkar, Taufik, Darmadi Darmadi, Cennikon Pakpahan, and Adriansyah Lubis. "Epigenetic modifications in hepatocellular carcinoma: A literature review." Rawal Medical Journal 50 (2025), 514-517. doi:10.5455/rmj.20240425033740



MLA (The Modern Language Association) Style

Sungkar, Taufik, Darmadi Darmadi, Cennikon Pakpahan, and Adriansyah Lubis. "Epigenetic modifications in hepatocellular carcinoma: A literature review." Rawal Medical Journal 50.2 (2025), 514-517. Print. doi:10.5455/rmj.20240425033740



APA (American Psychological Association) Style

Sungkar, T., Darmadi, . D., Pakpahan, . C. & Lubis, . A. (2025) Epigenetic modifications in hepatocellular carcinoma: A literature review. Rawal Medical Journal, 50 (2), 514-517. doi:10.5455/rmj.20240425033740