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Case Report 
RMJ. 2025; 50(2): 547-549


A case of giant cell arteritis with subsequent ischemic stroke: Highlighting treatment challenges

Binish Zain, Soman Rasool, Ashar Ekhlaq Ahmed, Mehnaz Mehmood.


Abstract
Abstract:
We present the case of a 74-year-old male with Diabetes Mellitus and Angina who was diagnosed with Giant Cell Arteritis (GCA) but received suboptimal treatment with low-dose prednisolone despite persistently elevated erythrocyte sedimentation rate (ESR). This led to progressive symptoms, including headache, jaw claudication, and eventual vision loss. He presented with severe headaches, blurred vision, and disorientation. Imaging and ultrasound confirmed GCA, and treatment with high-dose IV methylprednisolone initially improved symptoms. However, he developed acute ischemic infarctions in the posterior circulation, followed by complications such as vertigo, bilateral visual loss, and encephalopathy. Despite aggressive management with dual antiplatelet therapy and corticosteroids, the patient succumbed to complications. This case highlights the importance of timely and adequate GCA treatment, especially in patients with comorbidities. The risk of ischemic stroke, reported in 3-7% of GCA patients, underscores the need for vigilant monitoring and appropriate therapeutic dosing to prevent severe outcomes.

Key words: Giant cell arteritis, ischemic stroke, large-vessel vasculitis, cerebrovascular complications.


 
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How to Cite this Article
Pubmed Style

Zain B, Rasool S, Ahmed AE, Mehmood M. A case of giant cell arteritis with subsequent ischemic stroke: Highlighting treatment challenges. RMJ. 2025; 50(2): 547-549.

Web Style

Zain B, Rasool S, Ahmed AE, Mehmood M. A case of giant cell arteritis with subsequent ischemic stroke: Highlighting treatment challenges. https://www.rmj.org.pk/?mno=236266 [Access: May 12, 2025].

AMA (American Medical Association) Style

Zain B, Rasool S, Ahmed AE, Mehmood M. A case of giant cell arteritis with subsequent ischemic stroke: Highlighting treatment challenges. RMJ. 2025; 50(2): 547-549.


Vancouver/ICMJE Style

Zain B, Rasool S, Ahmed AE, Mehmood M. A case of giant cell arteritis with subsequent ischemic stroke: Highlighting treatment challenges. RMJ. (2025), [cited May 12, 2025]; 50(2): 547-549.


Harvard Style

Zain, B., Rasool, . S., Ahmed, . A. E. & Mehmood, . M. (2025) A case of giant cell arteritis with subsequent ischemic stroke: Highlighting treatment challenges. RMJ, 50 (2), 547-549.


Turabian Style

Zain, Binish, Soman Rasool, Ashar Ekhlaq Ahmed, and Mehnaz Mehmood. 2025. A case of giant cell arteritis with subsequent ischemic stroke: Highlighting treatment challenges. Rawal Medical Journal, 50 (2), 547-549.


Chicago Style

Zain, Binish, Soman Rasool, Ashar Ekhlaq Ahmed, and Mehnaz Mehmood. "A case of giant cell arteritis with subsequent ischemic stroke: Highlighting treatment challenges." Rawal Medical Journal 50 (2025), 547-549.


MLA (The Modern Language Association) Style

Zain, Binish, Soman Rasool, Ashar Ekhlaq Ahmed, and Mehnaz Mehmood. "A case of giant cell arteritis with subsequent ischemic stroke: Highlighting treatment challenges." Rawal Medical Journal 50.2 (2025), 547-549. Print.


APA (American Psychological Association) Style

Zain, B., Rasool, . S., Ahmed, . A. E. & Mehmood, . M. (2025) A case of giant cell arteritis with subsequent ischemic stroke: Highlighting treatment challenges. Rawal Medical Journal, 50 (2), 547-549.


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