ISSN 0303-5212
 
2026, Vol: 51, Issue: 2
51 / 2Current Issue Online FirstArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

Author_Certificate-old
Bank Reciept

Original Research 


Efficacy of topical DMSO in macular amyloidosis

Tayyaba Iqbal, Naseema Kapadia, Saher Ather, Sadia Iqbal, Maria Mansoor, Shahmoona Faisal, Nadia Farooq, Feroza Fatima.


Abstract
Objective: To evaluate the efficacy of 50% topical Dimethlsulfoxide (DMSO) in Macular Amyloidosis.
Methodology: This cross sectional, interventional study was conducted in dermatology department, Abbasi Shaheed Hospital, Karachi, Pakistan from October 2011 to April 2012 . A total of 50 patients of ≥16 years of age, clinically diagnosed with Macular Amyloidosis were included via purposive sampling. They were advised to apply thin layer of 50% DMSO on affected area at night. At presentation, patients were assessed for presence of pigmentation and pruritis was graded subjectively by patient on 10 cm. visual analogue scale (VAS) as absent (0), mild (1-3), moderate (4-7) and severe (˃7). Successful response was recorded at end of 3rd month of therapy in terms of complete resolution of pigmentation and zero or mild pruritis.
Results: Among 50 patients, moderate pruritis was present in 21 (42%) patients while severe pruritis in 24 (58%). Pigmentation was present in all 50 (100%) patients. At end of 3 months treatment, pruritis resolved to absent (0) in 49(98%) patients and only 1 patient (2%) had moderate pruritis. Whereas, pigmentation was resolved in only 4 (8%) patients.
Conclusion: By DMSO application, satisfactory response was observed in itching. We hope to observe response in pigmentation also on long term treatment

Key words: Macular Amyloidosis (M.A), dimethylsulfoxide (DMSO), pruritis, pigmentation.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Tayyaba Iqbal
Articles by Naseema Kapadia
Articles by Saher Ather
Articles by Sadia Iqbal
Articles by Maria Mansoor
Articles by Shahmoona Faisal
Articles by Nadia Farooq
Articles by Feroza Fatima
on Google
on Google Scholar

How to Cite this Article
Pubmed Style

Iqbal T, Kapadia N, Ather S, Iqbal S, Mansoor M, Faisal S, Farooq N, Fatima F. Efficacy of topical DMSO in macular amyloidosis. RMJ. 2017; 42(1): 43-47.

Web Style

Iqbal T, Kapadia N, Ather S, Iqbal S, Mansoor M, Faisal S, Farooq N, Fatima F. Efficacy of topical DMSO in macular amyloidosis. https://www.rmj.org.pk/?mno=238116 [Access: June 27, 2026].

AMA (American Medical Association) Style

Iqbal T, Kapadia N, Ather S, Iqbal S, Mansoor M, Faisal S, Farooq N, Fatima F. Efficacy of topical DMSO in macular amyloidosis. RMJ. 2017; 42(1): 43-47.


Vancouver/ICMJE Style

Iqbal T, Kapadia N, Ather S, Iqbal S, Mansoor M, Faisal S, Farooq N, Fatima F. Efficacy of topical DMSO in macular amyloidosis. RMJ. (2017), [cited June 27, 2026]; 42(1): 43-47.


Harvard Style

Iqbal, T., Kapadia, . N., Ather, . S., Iqbal, . S., Mansoor, . M., Faisal, . S., Farooq, . N. & Fatima, . F. (2017) Efficacy of topical DMSO in macular amyloidosis. RMJ, 42 (1), 43-47.


Turabian Style

Iqbal, Tayyaba, Naseema Kapadia, Saher Ather, Sadia Iqbal, Maria Mansoor, Shahmoona Faisal, Nadia Farooq, and Feroza Fatima. 2017. Efficacy of topical DMSO in macular amyloidosis. Rawal Medical Journal, 42 (1), 43-47.


Chicago Style

Iqbal, Tayyaba, Naseema Kapadia, Saher Ather, Sadia Iqbal, Maria Mansoor, Shahmoona Faisal, Nadia Farooq, and Feroza Fatima. "Efficacy of topical DMSO in macular amyloidosis." Rawal Medical Journal 42 (2017), 43-47.


MLA (The Modern Language Association) Style

Iqbal, Tayyaba, Naseema Kapadia, Saher Ather, Sadia Iqbal, Maria Mansoor, Shahmoona Faisal, Nadia Farooq, and Feroza Fatima. "Efficacy of topical DMSO in macular amyloidosis." Rawal Medical Journal 42.1 (2017), 43-47. Print.


APA (American Psychological Association) Style

Iqbal, T., Kapadia, . N., Ather, . S., Iqbal, . S., Mansoor, . M., Faisal, . S., Farooq, . N. & Fatima, . F. (2017) Efficacy of topical DMSO in macular amyloidosis. Rawal Medical Journal, 42 (1), 43-47.


Author LoginReviewer LoginEditorial PoliciesConflict of Interest PolicyPlagiarism PolicyAdvertising Policy

About Rawal Medical Journal

Publication, subscription and Editorial office PMA House G/220-B Liaquat Road, Rawalpindi. Phone: 051-555-9812, Fax: 051-553-7088 Email: drnkhokhar@ya ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information