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2025, Vol: 50, Issue: 4
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Role of the CHA2DS2VASc Score as a short-term clinical predictor in chronic kidney disease patients undergoing regular hemodialysis

M. Feldi Gazaly, Bayu Rusfandi Nasution.


Abstract
Objective: To evaluate the role of the CHA2DS2 VASc score as a short term clinical predictor in chronic kidney disease (CKD) patients undergoing regular haemodialysis.
Methodology: This retrospective cohort study analysed CKD patients undergoing regular haemodialysis at a tertiary hospital in Medan, Indonesia. Patients were categorized into low (0-1), moderate (2-3), and high-risk (4-9) groups based on their CHA2DS2-VASc scores. One-year mortality was the primary outcome, assessed using survival analysis and multivariate regression.
Results: Higher CHA2DS2-VASc scores ≥4 were associated with older age, increased comorbidities, and elevated inflammatory markers. Survival analysis showed a significant correlation between higher scores and increased mortality risk (HR 5.602, p<0.001), although multivariate analysis did not identify independent predictors of mortality. Laboratory findings varied across risk groups, with significant differences in CRP, uric acid, and calcium levels.
Conclusion: The CHA2DS2-VASc score may serve as a useful tool for mortality risk stratification in haemodialysis patients. However, its predictive value remains uncertain due to study limitations, including a single-centre design and small sample size. Further research with larger cohorts and additional biomarkers is needed to enhance its clinical applicability in CKD populations.

Key words: Chronic kidney disease, hemodialysis, CHA2DS2VASC score, mortality risk.


 
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Pubmed Style

Gazaly MF, Nasution BR. Role of the CHA2DS2VASc Score as a short-term clinical predictor in chronic kidney disease patients undergoing regular hemodialysis. RMJ. 2025; 50(3): 596-600. doi:10.5455/rmj.20250202011417

Web Style

Gazaly MF, Nasution BR. Role of the CHA2DS2VASc Score as a short-term clinical predictor in chronic kidney disease patients undergoing regular hemodialysis. https://www.rmj.org.pk/?mno=240688 [Access: October 30, 2025]. doi:10.5455/rmj.20250202011417

AMA (American Medical Association) Style

Gazaly MF, Nasution BR. Role of the CHA2DS2VASc Score as a short-term clinical predictor in chronic kidney disease patients undergoing regular hemodialysis. RMJ. 2025; 50(3): 596-600. doi:10.5455/rmj.20250202011417


Vancouver/ICMJE Style

Gazaly MF, Nasution BR. Role of the CHA2DS2VASc Score as a short-term clinical predictor in chronic kidney disease patients undergoing regular hemodialysis. RMJ. (2025), [cited October 30, 2025]; 50(3): 596-600. doi:10.5455/rmj.20250202011417


Harvard Style

Gazaly, M. F. & Nasution, . B. R. (2025) Role of the CHA2DS2VASc Score as a short-term clinical predictor in chronic kidney disease patients undergoing regular hemodialysis. RMJ, 50 (3), 596-600. doi:10.5455/rmj.20250202011417


Turabian Style

Gazaly, M. Feldi, and Bayu Rusfandi Nasution. 2025. Role of the CHA2DS2VASc Score as a short-term clinical predictor in chronic kidney disease patients undergoing regular hemodialysis. Rawal Medical Journal, 50 (3), 596-600. doi:10.5455/rmj.20250202011417


Chicago Style

Gazaly, M. Feldi, and Bayu Rusfandi Nasution. "Role of the CHA2DS2VASc Score as a short-term clinical predictor in chronic kidney disease patients undergoing regular hemodialysis." Rawal Medical Journal 50 (2025), 596-600. doi:10.5455/rmj.20250202011417


MLA (The Modern Language Association) Style

Gazaly, M. Feldi, and Bayu Rusfandi Nasution. "Role of the CHA2DS2VASc Score as a short-term clinical predictor in chronic kidney disease patients undergoing regular hemodialysis." Rawal Medical Journal 50.3 (2025), 596-600. Print. doi:10.5455/rmj.20250202011417


APA (American Psychological Association) Style

Gazaly, M. F. & Nasution, . B. R. (2025) Role of the CHA2DS2VASc Score as a short-term clinical predictor in chronic kidney disease patients undergoing regular hemodialysis. Rawal Medical Journal, 50 (3), 596-600. doi:10.5455/rmj.20250202011417


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