Prevalence of hypertriglyceridemia in beta thalassemia major and intermedia patients: a study from public-sector thalassemia center

Sundas Ali; Huma Abdul Shakoor; Hina Bilal; Armaghana Qamar Khan; Maha Tariq Kiani; Samina Tufail Amanat

2026, Vol: 51, Issue: 3

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RMJ. 2026; 51(3): 658-6261

Prevalence of hypertriglyceridemia in beta thalassemia major and intermedia patients: a study from public-sector thalassemia center

Sundas Ali, Huma Abdul Shakoor, Hina Bilal, Armaghana Qamar Khan, Maha Tariq Kiani, Samina Tufail Amanat.

Abstract
Objective: To determine the frequency of hypertriglyceridemia in beta thalassemia patients and to compare triglyceride values in beta-thalassemia major and beta thalassemia intermedia patients.
Methodology: A three-month prospective cross-sectional study from February 2024 to April 2024 was conducted at the Department of Pathology, P.I.M.S, in collaboration with Thalassemia Center. It included 100 thalassemic patients, comprising 55 Beta Thalassemia Major and 45 Beta Thalassemia Intermedia. Serum triglyceride levels were measured using Roche Chemistry Autoanalyzer after an overnight fast. Data analysis was done on SPSS.
Results: Hypertriglyceridemia prevalence was 26%, with 12% in β-TM and 14% in β-TI. Mean triglyceride levels were 135.0±52.6 mg/dl overall, 135.2±57.1 mg/dl in β-TM, and 134.71±47.2 mg/dl in β-TI (p=0.95). Among patients with hypertriglyceridemia, 6 (50%) of β-TM and 10 (71.4%) of β-TI had borderline high TG levels (150-199 mg/dl); while 6 (50%) of β-TM and 4 (28.5%) of β-TI had high TG levels (>500 mg/dl).
Conclusion: This study found a significant prevalence of hypertriglyceridemia in beta thalassemia major and intermedia patients, highlighting the need for timely diagnosis and tailored management strategies to address this important aspect of their health profile.

Key words: Thalassemia major, thalassemia intermedia, triglyceride, atherosclerosis, hypertriglyceridemia.

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How to Cite this Article

Pubmed Style

Ali S, Shakoor HA, Bilal H, Khan AQ, Kiani MT, Amanat ST. Prevalence of hypertriglyceridemia in beta thalassemia major and intermedia patients: a study from public-sector thalassemia center. RMJ. 2026; 51(3): 658-6261.

Web Style

Ali S, Shakoor HA, Bilal H, Khan AQ, Kiani MT, Amanat ST. Prevalence of hypertriglyceridemia in beta thalassemia major and intermedia patients: a study from public-sector thalassemia center. https://www.rmj.org.pk/?mno=233599 [Access: August 19, 2026].

AMA (American Medical Association) Style

Ali S, Shakoor HA, Bilal H, Khan AQ, Kiani MT, Amanat ST. Prevalence of hypertriglyceridemia in beta thalassemia major and intermedia patients: a study from public-sector thalassemia center. RMJ. 2026; 51(3): 658-6261.

Vancouver/ICMJE Style

Harvard Style

Ali, S., Shakoor, . H. A., Bilal, . H., Khan, . A. Q., Kiani, . M. T. & Amanat, . S. T. (2026) Prevalence of hypertriglyceridemia in beta thalassemia major and intermedia patients: a study from public-sector thalassemia center. RMJ, 51 (3), 658-6261.

Turabian Style

Ali, Sundas, Huma Abdul Shakoor, Hina Bilal, Armaghana Qamar Khan, Maha Tariq Kiani, and Samina Tufail Amanat. 2026. Prevalence of hypertriglyceridemia in beta thalassemia major and intermedia patients: a study from public-sector thalassemia center. Rawal Medical Journal, 51 (3), 658-6261.

Chicago Style

Ali, Sundas, Huma Abdul Shakoor, Hina Bilal, Armaghana Qamar Khan, Maha Tariq Kiani, and Samina Tufail Amanat. "Prevalence of hypertriglyceridemia in beta thalassemia major and intermedia patients: a study from public-sector thalassemia center." Rawal Medical Journal 51 (2026), 658-6261.

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