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Original Research 
RMJ. 2024; 49(3): 587-591


Oxidative stress and antioxidant Vitamin C among cataract patients: A case control study

Ghazala Panhwar, Kiran Fatima Mehboob Ali, Aqsa Ejaz, Haseeb Ali, Ejaz Latif, Muneer Azhar Choudry.


Abstract
Objective: To compare mean of blood antioxidant Vitamin-C and oxidative stress marker (MDA) among cases of aging cataract and controls.
Methodology: This case control study was conducted at Ophthalmology Department of Bahawalpur Medical College and Teaching Hospital, Bahawalpur. There were total 40 aging cataract and 40 controls after matching age & demographics. The data were analyzed on SPSS version 27. Correlation coefficient was performed to compare mean of blood antioxidant vitamins (C) and MDA among cases of aging cataract and controls.
Result: Mean age was 61.19+5.65 years in cataract and 52.50+9.71 years in controls. In cases, mean weight was 66.42+12.86 kg and mean height was 1.65+0.08 meter. Mean waist was 93.74+14.44 cm in cataract patients. In cases, mean of BMI was 24.25+4.93 and 21.81±4.56 in control. The weight, height, waist and BMI were higher in cases than controls. Mean random blood sugar was 112.58+34.55 mg/dl and antioxidant vitamin C was low (32.15+16.62) in cataract patients. The MDA was higher in cases than controls.

Conclusion: Serum vitamin C level is depleted among cataract. Oxidative stress MDA was significantly high in cataract patients as compared to control. Hence, oxidative stress has important initiating role in cataract formation. It highlights the importance of vitamin-C supplements to prevent age related cataract.

Key words: Antioxidant, cataract patients, oxidative stress, Vitamin-C.


 
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How to Cite this Article
Pubmed Style

Panhwar G, Ali KFM, Ejaz A, Ali H, Latif E, Choudry MA. Oxidative stress and antioxidant Vitamin C among cataract patients: A case control study. RMJ. 2024; 49(3): 587-591.

Web Style

Panhwar G, Ali KFM, Ejaz A, Ali H, Latif E, Choudry MA. Oxidative stress and antioxidant Vitamin C among cataract patients: A case control study. https://www.rmj.org.pk/?mno=170966 [Access: September 12, 2024].

AMA (American Medical Association) Style

Panhwar G, Ali KFM, Ejaz A, Ali H, Latif E, Choudry MA. Oxidative stress and antioxidant Vitamin C among cataract patients: A case control study. RMJ. 2024; 49(3): 587-591.


Vancouver/ICMJE Style

Panhwar G, Ali KFM, Ejaz A, Ali H, Latif E, Choudry MA. Oxidative stress and antioxidant Vitamin C among cataract patients: A case control study. RMJ. (2024), [cited September 12, 2024]; 49(3): 587-591.


Harvard Style

Panhwar, G., Ali, . K. F. M., Ejaz, . A., Ali, . H., Latif, . E. & Choudry, . M. A. (2024) Oxidative stress and antioxidant Vitamin C among cataract patients: A case control study. RMJ, 49 (3), 587-591.


Turabian Style

Panhwar, Ghazala, Kiran Fatima Mehboob Ali, Aqsa Ejaz, Haseeb Ali, Ejaz Latif, and Muneer Azhar Choudry. 2024. Oxidative stress and antioxidant Vitamin C among cataract patients: A case control study. Rawal Medical Journal, 49 (3), 587-591.


Chicago Style

Panhwar, Ghazala, Kiran Fatima Mehboob Ali, Aqsa Ejaz, Haseeb Ali, Ejaz Latif, and Muneer Azhar Choudry. "Oxidative stress and antioxidant Vitamin C among cataract patients: A case control study." Rawal Medical Journal 49 (2024), 587-591.


MLA (The Modern Language Association) Style

Panhwar, Ghazala, Kiran Fatima Mehboob Ali, Aqsa Ejaz, Haseeb Ali, Ejaz Latif, and Muneer Azhar Choudry. "Oxidative stress and antioxidant Vitamin C among cataract patients: A case control study." Rawal Medical Journal 49.3 (2024), 587-591. Print.


APA (American Psychological Association) Style

Panhwar, G., Ali, . K. F. M., Ejaz, . A., Ali, . H., Latif, . E. & Choudry, . M. A. (2024) Oxidative stress and antioxidant Vitamin C among cataract patients: A case control study. Rawal Medical Journal, 49 (3), 587-591.


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