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Original Research 
RMJ. 2024; 49(2): 383-386


Association of physical activity with Mitochondrial DNA Copy Number in Eveningness Chronotypes

Madeeha Maqsood, Shazia Ali, Suhaib Ahmed, Shagufta Feroz.


Abstract
Objective: To determine the association of physical activity with mitochondrial DNA copy number (mtDNA-CN) in eveningness chronotype.
Methodology: In this cross-sectional analytical study, 80 eveningness chronotypes were recruited by distributing the morningness-eveningness questionnaire (MEQ). Physical activity levels of participants were assessed by using International Physical Activity Questionnaire (IPAQ), and 2 groups were made. Group A included active (n=40) and Group B included inactive participants (n=40). Mitochondrial DNA copy number of all the participants was determined by quantitative polymerase chain reaction (PCR). Data were analyzed using SPSS 27.
Results: A total of 80 participants (Male=30, Female=50) with mean age of 24.27±6.91 years (range 18-45 years) were included in the study. Mean mitochondrial DNA copy number (log-transformed) was significantly higher in active participants as compared to inactive ones (p<0.001).
Conclusion: Participants who were physically active had higher mitochondrial DNA copy number indicating less mitochondrial DNA damage and improved mitochondrial function despite being eveningness chronotype.

Key words: Mitochondria, mitochondrial DNA, oxidative stress, chronotype.


 
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How to Cite this Article
Pubmed Style

Maqsood M, Ali S, Ahmed S, Feroz S. Association of physical activity with Mitochondrial DNA Copy Number in Eveningness Chronotypes. RMJ. 2024; 49(2): 383-386.

Web Style

Maqsood M, Ali S, Ahmed S, Feroz S. Association of physical activity with Mitochondrial DNA Copy Number in Eveningness Chronotypes. https://www.rmj.org.pk/?mno=158993 [Access: April 25, 2024].

AMA (American Medical Association) Style

Maqsood M, Ali S, Ahmed S, Feroz S. Association of physical activity with Mitochondrial DNA Copy Number in Eveningness Chronotypes. RMJ. 2024; 49(2): 383-386.


Vancouver/ICMJE Style

Maqsood M, Ali S, Ahmed S, Feroz S. Association of physical activity with Mitochondrial DNA Copy Number in Eveningness Chronotypes. RMJ. (2024), [cited April 25, 2024]; 49(2): 383-386.


Harvard Style

Maqsood, M., Ali, . S., Ahmed, . S. & Feroz, . S. (2024) Association of physical activity with Mitochondrial DNA Copy Number in Eveningness Chronotypes. RMJ, 49 (2), 383-386.


Turabian Style

Maqsood, Madeeha, Shazia Ali, Suhaib Ahmed, and Shagufta Feroz. 2024. Association of physical activity with Mitochondrial DNA Copy Number in Eveningness Chronotypes. Rawal Medical Journal, 49 (2), 383-386.


Chicago Style

Maqsood, Madeeha, Shazia Ali, Suhaib Ahmed, and Shagufta Feroz. "Association of physical activity with Mitochondrial DNA Copy Number in Eveningness Chronotypes." Rawal Medical Journal 49 (2024), 383-386.


MLA (The Modern Language Association) Style

Maqsood, Madeeha, Shazia Ali, Suhaib Ahmed, and Shagufta Feroz. "Association of physical activity with Mitochondrial DNA Copy Number in Eveningness Chronotypes." Rawal Medical Journal 49.2 (2024), 383-386. Print.


APA (American Psychological Association) Style

Maqsood, M., Ali, . S., Ahmed, . S. & Feroz, . S. (2024) Association of physical activity with Mitochondrial DNA Copy Number in Eveningness Chronotypes. Rawal Medical Journal, 49 (2), 383-386.


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